Strong Evidence Reinforces the Benefits of Plant-Based Diets for Heart Health

Recent research from Unity Health Toronto and the University of Toronto provides compelling evidence supporting the cardioprotective effects of the plant-based Portfolio Diet. Two large-scale studies demonstrate that following this diet can significantly reduce the risk of cardiovascular disease (CVD) and overall mortality, emphasizing its value for diverse populations.

The first study, published in BMC Medicine, analyzed data from nearly 15,000 Americans, revealing that adherence to the Portfolio Diet was linked to a substantial decrease in death rates due to heart disease, coronary heart disease, and other causes. This diet, developed in 2003 by Professor David Jenkins at U of T, includes key food components such as nuts, plant-based proteins like beans or tofu, viscous fiber sources such as oats and apples, and foods rich in phytosterols and monounsaturated fats like enriched margarine or oils. Participants earning higher points for consuming these foods—and reducing saturated fats—showed lower levels of risk factors such as blood lipids, inflammation, and blood sugar.

Even moderate compliance with the diet contributed to notable health benefits, including a 12% lower risk of cardiovascular disease, a 14% reduction in coronary heart disease risk, and a 12% decrease in all-cause mortality. The research was led by John Sievenpiper from St. Michael’s Hospital, who highlighted how more nuanced dietary assessments—considering cooking fats and food preparation—provided a clearer understanding of the diet’s impacts.

A second study focused on a younger, ethnically diverse group in their 20s, using data from the Toronto Nutrigenomics and Health Study. Published in BMC Public Health, this research found that even in a low-risk cohort, greater adherence to the Portfolio Diet correlated with lower LDL cholesterol, total cholesterol, and blood pressure. These early dietary habits could delay the development of cardiovascular issues by up to 13 years, making early intervention crucial. Researchers suggest that simple, accessible foods like nuts, fruits, and berries can integrally support long-term heart health.

Both studies underscore the importance of adopting a plant-based, nutrient-rich diet early in life and maintaining moderate adherence. The evidence advocates for incorporating these dietary patterns into everyday life, especially during key transitional phases, to promote lifelong cardiovascular health.

Source: https://medicalxpress.com/news/2025-06-evidence-underscores-power-based-diet.html