Cycling as a Potential Therapy for Parkinson's Disease: Restoring Neural Connections

Cycling May Help Repair Brain Damage in Parkinson’s Disease

Scientists have uncovered promising evidence that cycling can aid in restoring neural connections damaged by Parkinson’s disease. A recent study published in Clinical Neurophysiology demonstrated that just 12 cycling sessions over four weeks produced measurable changes in brain activity related to motor control.

Parkinson’s disease affects over 10 million people worldwide, impairing movement due to disruptions in the central nervous system, including the brain. Dr. Aasef Shaikh, lead researcher, explained that exercise might induce brain plasticity — the brain’s ability to rewire itself — outside of the traditionally implicated basal ganglia.

In the study, nine participants with Parkinson’s, all with pre-implanted deep brain stimulation devices, engaged in adaptive cycling exercises. The bike adjusted resistance based on individual effort, providing a personalized workout. Post-intervention, brain signals showed significant improvements in motor-related activity, indicating potential for exercise to promote neural recovery.

Expert opinions from neurologists emphasize that exercise has long been known to benefit Parkinson’s symptoms, but this study sheds light on how these benefits occur at a circuit level. The findings advocate for continued physical activity as a key component in managing Parkinson’s and suggest exploring other modalities like magnetic or electric stimulation.

This research underscores the importance of sustained, long-term exercise for neuroplasticity and highlights the potential for non-pharmacological interventions to modify disease progression.