Long-Term Impact of Post-Stroke Depression on Patient Health and Survival

New research shows that depression after stroke can impact health and survival for up to a decade, highlighting the importance of ongoing mental health support in stroke recovery.
Recent research highlights the significant long-term effects of depression following a stroke. A study conducted by King's College London analyzed data from over 2,500 stroke survivors in the South London Stroke Register, revealing that depression occurring within three months after a stroke (post-stroke depression, PSD) can influence health outcomes for up to ten years. Notably, 36% of participants exhibited depression symptoms three months post-stroke. Those with persistent depression faced nearly three times higher likelihood of long-term physical disability and a 30% increased risk of mortality within a decade. Moreover, ongoing depression was linked to reduced ability to perform daily activities, decreased quality of life, and higher chances of experiencing another stroke. Conversely, patients who recovered from depression within the first year had health outcomes comparable to those who never experienced PSD.
Recovery from depression during this period was associated with better physical and mental health, decreased mortality, and improved functional outcomes. The study emphasizes the importance of sustained mental health support in stroke rehabilitation, as depression remains a critical predictor of long-term health risks. Experts from the research team stressed that depression should not be overlooked years after a stroke, and ongoing treatment could significantly enhance patients' quality of life.
While current stroke care focuses mainly on physical recovery, these findings advocate for integrating long-term mental health interventions. Addressing depression early and supporting its recovery can have broader health benefits, including lowering the risk of future strokes and improving overall well-being. The researchers hope this evidence will encourage healthcare providers to implement comprehensive, long-term mental health strategies in stroke management.
Source: https://medicalxpress.com/news/2025-05-depression-affect-health-decade.html
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