Increased Use of Mental Health Medications Among Cancer Survivors

Recent research highlights that U.S. cancer survivors are significantly more inclined to use medications for depression and anxiety compared to individuals without a history of cancer. A comprehensive study published on August 19, 2025, in JAMA Network Open, analyzed data from the National Health Interview Survey collected between 2016 and 2018, involving over 5,000 adult cancer survivors along with nearly 50,000 individuals without cancer.

The study, led by Daniela Miro-Rivera from Yale University, aimed to explore how sociodemographic factors influence the usage of antidepressants and anxiolytics among cancer survivors. After adjusting for variables such as age, race, and insurance status, the findings revealed that cancer survivors have higher odds of taking these medications: with an adjusted odds ratio (aOR) of 1.32 for antidepressants and 1.38 for anxiolytics, relative to the general population.

Interestingly, racial disparities were observed—with non-Hispanic Black survivors exhibiting lower odds of medication use (aOR of 0.60 for antidepressants and 0.63 for anxiolytics) compared to non-Hispanic White survivors. Additionally, those on Medicare or Medicaid were more likely to use these medications than those with private insurance, with aORs of 2.20 and 1.83, respectively. The type of cancer also played a role; individuals with a history of brain cancer were significantly more likely to take antidepressants (aOR 5.59), and those with pancreatic cancer had higher chances of using both antidepressants (aOR 5.30) and anxiolytics (aOR 6.74).

The researchers emphasized the importance of equitable mental health care for cancer survivors, as depression and anxiety can adversely affect treatment outcomes. They advocate for ensuring access to mental health support regardless of sociodemographic factors.

This study underscores the mental health challenges faced by cancer survivors and the importance of addressing disparities to improve their overall well-being.

Source: https://medicalxpress.com/news/2025-08-cancer-survivors-rx-mental-health.html