Tailoring Chronic Pain Treatment Through a Data-Driven Approach

Managing chronic pain requires a nuanced understanding of how individual factors influence perception and behavior. Recent research highlights the potential of data-driven methods to customize treatment plans for each patient, based on their unique psychological and physiological responses.

Gita Nadinda, a Ph.D. candidate at Leiden University, has explored the complex relationship between expectations, avoidance behaviors, and somatic sensations like pain and itch. Her studies show that negative expectations do not always necessarily lead to avoidance behaviors, challenging traditional models like the fear-avoidance theory. In controlled experiments, participants often preferred to endure some pain or itch rather than avoid activities that could reduce discomfort, indicating individual variability in response to expected discomfort.

Nadinda's network analysis of patients with chronic low back pain involved collecting real-time data on pain, mood, and avoidance. The results revealed significant differences at the individual level, emphasizing that a one-size-fits-all approach to treatment may be less effective. Instead, tailored therapies that consider individual data patterns could improve outcomes.

This personalized approach reflects a broader shift in healthcare, where understanding the specific psychological and behavioral factors influencing pain can help develop more effective interventions. Acknowledging that some discomfort may be worth enduring for the sake of personal joy or achievement is key to managing chronic conditions effectively.

Her work underscores the importance of considering individual differences in pain perception and avoidance. As Nadinda notes, sometimes enduring pain is a conscious choice that balances individual costs and benefits, similar to her own experience with allergies.

For more insights, see her dissertation "Nexus Uncovered: On the Relations Between Expectancy, Avoidance, and Somatic Sensations". This research encourages adopting personalized, data-driven strategies to better understand and treat chronic pain and itch.

Source: https://medicalxpress.com/news/2025-09-chronic-pain-driven-approach-tailor.html