One in Four People Expected to Develop Heart Failure During Their Lifetime

Recent studies highlight a rising concern in cardiovascular health, revealing that approximately 25% of individuals will face the development of heart failure during their lifetime. According to a comprehensive 2025 report published in the Journal of Cardiac Failure, the risk of heart failure has increased significantly, with projections estimating that by 2030, nearly 8.7 million Americans could be affected. This condition contributes notably to cardiovascular mortality, accounting for 45% of cardiovascular deaths in the United States in 2022. Epidemiological data indicate higher incidence and prevalence rates among Black populations compared to other racial and ethnic groups, underscoring disparities in health outcomes.

The report emphasizes that Black, American Indian, and Alaska Native populations bear the highest mortality rates associated with heart failure. Managing the condition remains costly, with estimates suggesting that by 2050, heart failure-related expenses could reach approximately $858 billion. Despite advancements in treatment, less than 25% of eligible patients with reduced ejection fraction are receiving guideline-recommended quadruple medical therapy.

Experts, including Dr. Gregg C. Fonarow from UCLA, emphasize that heart failure is a growing epidemic impacting millions across demographic lines. The increase in mortality rates coupled with underutilization of effective therapies underscores the urgent need for improved strategies in prevention, early diagnosis, and comprehensive treatment. Addressing these issues is critical to reversing trends and reducing the profound health and economic burden associated with heart failure.

Source: https://medicalxpress.com/news/2025-10-individuals-heart-failure-lifetime.html