Novo Nordisk Acquires US BioTech Leader Akero for $4.7 Billion to Advance Metabolic Disease Treatments

Novo Nordisk has acquired US biotech firm Akero Therapeutics for $4.7 billion, aiming to develop groundbreaking treatments for metabolic diseases like fatty liver and obesity. The deal emphasizes innovation in managing liver damage and expanding therapies for millions worldwide.
On October 9, 2025, Novo Nordisk announced a significant strategic move by acquiring the US-based biotechnology company Akero Therapeutics for a substantial sum of $4.7 billion. This acquisition aims to bolster Novo Nordisk's portfolio in developing innovative therapies targeting metabolic diseases. Akero is known for its experimental drug efruxifermin, which shows promise in potentially reversing liver damage caused by fatty liver disease, a critical concern for individuals with obesity and type 2 diabetes.
The Danish pharmaceutical giant, renowned for its weight-loss medication Wegovy, highlighted that efruxifermin could become a leading treatment for MASH, a form of fatty liver disease affecting over 250 million people worldwide. MASH, which often accompanies obesity and diabetes, progresses silently but can lead to severe liver complications. Novo Nordisk's CEO Mike Doustdar emphasized that efruxifermin might revolutionize the management of this condition, offering hope for reversing liver damage.
The deal stipulates that Akero shareholders will receive $54 per share, a premium over the previous closing price of $46.49. Additionally, if efruxifermin secures regulatory approval for treating liver damage in MASH patients, shareholders will be eligible for an extra $6 per share. The strategic acquisition reflects Novo Nordisk’s long-term vision to expand its reach in the metabolic disease arena beyond weight management, aiming to develop treatments that address a broader spectrum of related health issues.
This move comes at a time when Novo Nordisk is restructuring to maintain its leading position in the competitive weight-loss market amid industry pressures. The company's investment in innovative drug development signals a commitment to improving outcomes for millions affected by obesity, diabetes, and related liver conditions.
Sources: https://medicalxpress.com/news/2025-10-novo-nordisk-buys-biotech-firm.html
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