Revised Seizure Classification for Epilepsy Focuses on Simplicity and Inclusivity
The ILAE has updated the seizure classification, simplifying terminology and promoting inclusivity for better diagnosis and research in epilepsy care.
The International League Against Epilepsy (ILAE) has introduced a revised operational classification of epileptic seizures, enhancing clarity and practicality for healthcare professionals. Building on the framework established in 2017, this update aims to standardize terminology across clinical settings and research environments worldwide.
Published in the journal Epilepsia, the new classification streamlines the previous 63 seizure types into four main categories—focal, generalized, unknown, and unclassified—and reduces the types to 21, making it easier to interpret and apply. Key modifications include removing 'onset' from seizure class names, differentiating between classifiers (which influence management) and descriptors (which detail specific features), and replacing 'awareness' with 'consciousness' for more precise classification.
Other notable changes involve replacing the motor/non-motor dichotomy with observable and non-observable manifestations, describing seizures based on the sequence of signs and symptoms instead of just the initial event, and recognizing epileptic negative myoclonus as a distinct seizure type. These updates aim to foster broader clinical adoption, improve communication among healthcare providers, and facilitate research and clinical trials.
The development of the new classification involved extensive review by a global working group, including systematic reviews and a consensus process during public comment periods. Special attention was paid to ensuring accurate translation into multiple languages, broadening accessibility. Seizures in neonates are addressed separately in another publication.
Overall, the revised classification is designed to be applicable across various levels of healthcare—from primary care to specialized epilepsy centers—enhancing diagnosis, management, and research efforts worldwide.
Source: https://medicalxpress.com/news/2025-05-seizure-classification-epilepsy-aims-simplicity.html
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