Increased Risk of COPD Among Individuals with Schizophrenia: New Research Findings

Recent research highlights a significant association between schizophrenia and a heightened risk of developing chronic obstructive pulmonary disease (COPD). Published in the July 2025 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, the study suggests a potential syndemic relationship, where shared socioeconomic, genetic, and environmental factors contribute to this connection. While smoking, which is considerably more prevalent among those with schizophrenia, partly explains the increased COPD risk, data indicates that other underlying factors also play a role. The underdiagnosis and undertreatment of COPD in people with schizophrenia are common issues, partly because respiratory symptoms are often misattributed to psychiatric conditions or noticed late due to inadequate medical care. Additionally, certain antipsychotic medications may impact respiratory health, increasing vulnerability to infections like pneumonia. Experts emphasize the need for primary care providers to be vigilant and regularly screen this population for respiratory illnesses. Implementing integrated healthcare services and reducing stigma could improve health outcomes and survival rates among this disadvantaged group. Recognizing the increased risk and ensuring thorough health assessments are essential steps toward better management and prevention of COPD in individuals with schizophrenia.