Understanding the Impact of Antipsychotic Medications on Oral Health
Research reveals that antipsychotic medications may cause significant oral health issues, including dry mouth, inflammation, and tooth loss. Regular dental assessments and collaboration between healthcare providers are essential for patient well-being.
Recent research conducted by the Department of Pharmacology at the University of the Basque Country has shed light on the adverse effects of antipsychotic medications on oral health. The study analyzed data from the European pharmacovigilance database, EudraVigilance, involving 5,633 reports that raised concerns about how these drugs may harm the mouth.
The findings indicate that the most common oral problems linked to antipsychotic use involve salivary flow disorders, such as excessive salivation and dry mouth. These conditions can lead to further oral health issues, including tooth decay, gum disease, inflammation of salivary glands and tongue, and even tooth loss. Researchers highlighted that these side effects are reported across various sources, including healthcare professionals, the pharmaceutical industry, and patients themselves.
Experts emphasize that while a causal relationship between antipsychotics and oral health problems has not been definitively established, there is a notable association indicating increased risk. Notably, reports involving adverse oral reactions are more frequent with antipsychotic drugs compared to other medications. This underscores the need for diligent oral health monitoring in patients prescribed these therapies.
Oral health is influenced by numerous factors, including the use of multiple medications, poor hygiene habits, substance abuse, and limited access to dental care—challenges often faced by individuals with mental health conditions. The research team advocates for systematic oral health assessments and better collaboration between mental health professionals and dental care providers. They also recommend preventive measures emphasizing good oral hygiene practices and regular dental checkups.
Overall, addressing oral health issues proactively can significantly improve the quality of life for patients on antipsychotic medications, helping reduce the burden of dental diseases associated with their treatment.
source: https://medicalxpress.com/news/2025-07-exploring-adverse-effects-antipsychotic-medications.html
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