Collagen-Enhanced Protein Bars Show Promise for Weight Loss and Health Improvements

Recent research presented at the European Congress on Obesity and published in the journal Nutrients suggests that protein bars enriched with collagen may serve as a safe and effective aid for weight management. Collagen, a connective tissue protein, when incorporated into dietary supplements, appears to promote significant weight loss and metabolic benefits in individuals with overweight or obesity.

A human clinical trial involving 64 participants aged between 20 and 65 years examined the effects of a collagen-enriched chocolate-flavored protein bar. Over a 12-week period, half of the participants consumed one bar before lunch and dinner, along with water, while adhering to a Mediterranean diet. The collagen used was derived from cows and treated to absorb extra water, causing it to swell notably in the stomach.

Results showed that those consuming the collagen bars lost twice as much weight as the control group, despite both groups maintaining similar calorie intake. Notably, the collagen group experienced a reduction in systolic blood pressure by 8 mm Hg, along with decreases in waist circumference, BMI, and liver fat index, indicating improved liver health. Additionally, the collagen group gained skeletal muscle mass, which is beneficial for metabolism, while muscle mass remained unchanged in the control group.

Participants in the collagen group also felt less hungry and more satiated, with higher levels of leptin, a hormone associated with satiety. Animal studies support these findings, showing collagen can reduce hunger hormones like ghrelin and expand significantly in the stomach without rapid digestion.

Importantly, the study reported no side effects, and participants rated the taste of the collagen bars highly. Researchers believe that the swelling of collagen in the stomach contributes to feeling full and suppressing appetite, leading to reduced calorie intake and weight loss. Collagen may also influence gut bacteria and support muscle growth, enhancing overall metabolic health.

The collagen protein bars evaluated in this study are already available commercially. The researchers are currently conducting larger trials to better understand the mechanisms of action, especially related to gut microbiota. This research highlights collagen's potential as an accessible, low-cost supplement to aid in weight loss and improve metabolic health.

Source: https://medicalxpress.com/news/2025-05-protein-bars-enriched-collagen-potential.html