Increased Risk of Bipolar Disorder in Multiracial Women During Pregnancy and Postpartum

A comprehensive study analyzing over 3.8 million women who gave birth in California has revealed that multiracial women face a higher likelihood of being diagnosed with bipolar disorder during the perinatal period. The research highlights significant disparities in mental health diagnoses across different racial and ethnic groups, with multiracial women, particularly those identifying as biracial Black and White, American Indian/Alaska Native and White, or Black and American Indian/Alaska Native, showing elevated risk.

The study found that although the multiracial women accounted for about 3.6% of the total sample, they represented nearly 9.7% of bipolar disorder cases. Among the over 19,260 women diagnosed with bipolar disorder, those identifying as biracial Black Asian, Black White, or Asian White had higher odds of diagnosis. Conversely, diagnoses among Hispanic/Latino and Asian women were disproportionately lower compared to their representation in the overall sample, indicating potential underdiagnosis or misinterpretation of symptoms possibly influenced by systemic biases.

This research underscores the importance of culturally sensitive screening practices during the perinatal period, as current screening tools for depression may not effectively detect bipolar disorder, which often manifests with depressive episodes before the onset of manic or hypomanic symptoms. Experts advocate for expanding screening protocols to include bipolar disorder, especially among high-risk groups.

Furthermore, the findings suggest that social determinants such as socioeconomic status, access to quality healthcare, and systemic racism could contribute to the heightened risk observed among multiracial women. Particularly, indigenous populations, including American Indian/Alaska Native groups, showed increased prevalence possibly related to multigenerational trauma and chronic stress exposure.

Given the diversity of California’s population, this study offers valuable insights into racial disparities in perinatal mental health. It emphasizes the need for tailored, culturally responsive interventions and improved screening procedures to ensure accurate diagnosis and effective treatment for all women during this vulnerable period. Further research is essential to better understand these disparities and enhance mental health support for multiracial and underserved populations.

Source: https://medicalxpress.com/news/2025-08-multiracial-women-greater-bipolar-disorder.html