Impact of Stress on Brain Function and the Potential of Non-Invasive Brain Stimulation
Recent research shows how acute stress affects brain functions and highlights the potential of non-invasive brain stimulation, especially targeting the ventromedial prefrontal cortex, to mitigate stress-induced cognitive impairments.
Stress significantly influences brain activity and overall physiological responses, affecting cognitive functions such as working memory and decision-making. A recent study from the Leibniz Research Center for Working Environment in Dortmund explored how acute psychological stress alters brain dynamics and whether non-invasive techniques can mitigate its adverse effects.
The researchers employed an innovative aversive video paradigm (AVP) to reliably induce stress in participants. During exposure to emotionally intense footage, subjects reported increased anxiety and negative emotions. Physiological indicators like elevated salivary cortisol levels and reduced heart rate variability confirmed the stress response, alongside observable changes in brain activity through EEG measures.
Findings revealed that stress impairs top-down control mechanisms while heightening bottom-up sensory processing. This imbalance leads to increased sensitivity to salient stimuli, difficulty focusing, impulsivity, and compromised decision-making—hallmarks consistent with stress-related cognitive disruptions. Notably, post-stress working memory tasks showed diminished performance, underscoring the cognitive toll of acute stress.
Further, the study investigated whether non-invasive brain stimulation could counteract these effects. Participants received transcranial direct current stimulation (tDCS) targeting specific prefrontal regions: the left dorsolateral prefrontal cortex (dlPFC) involved in working memory and the ventromedial prefrontal cortex (vmPFC), which plays a key role in emotional regulation. The strongest improvements in cognitive performance and reductions in cortisol levels were observed with vmPFC stimulation, highlighting its potential in stabilizing emotional and cognitive control under stress.
These findings suggest that targeted modulation of the vmPFC through non-invasive stimulation may help maintain cognitive function and regulate emotional responses during stressful periods, holding promise for therapeutic applications in stress-related disorders.
For more information, see the original research articles in the International Journal of Clinical and Health Psychology (2025). source: https://medicalxpress.com/news/2025-08-stress-affects-brain-invasive.html
Stay Updated with Mia's Feed
Get the latest health & wellness insights delivered straight to your inbox.
Related Articles
Long-Term Effects of Excessive Gaming on Adolescents, Study Finds
A new study reveals that excessive gaming affects 1 in 10 boys during adolescence, with long-term consequences for mental health, education, and relationships. Early intervention is key to prevention.
Addressing Rapid Weight Gain in Serious Mental Illness: The Need for Better Support
Serious mental illnesses like schizophrenia and bipolar disorder often lead to rapid, sustained weight gain, increasing risks for chronic diseases. Early intervention and integrated support are crucial to prevent long-term health complications.
A Positive Outlook on Life May Protect Against Memory Decline in Middle Age, 16-Year Study Finds
A 16-year study reveals that a positive outlook on life may help protect against memory decline in middle-aged adults, emphasizing the importance of mental well-being for cognitive health.
Feeling in Control Can Reduce Daily Stress, New Research Finds
Research shows that feeling more in control of daily stressors can significantly increase problem resolution and reduce overall stress, especially with age. Practical strategies to boost perceived control may improve mental well-being.