Innovative Ultrasound Method Enhances Early Diagnosis of Peripheral Artery Disease

A recent breakthrough in medical diagnostics, stemming from research by the University of Surrey, suggests a promising new approach for the early detection of peripheral artery disease (PAD). This condition, affecting up to 25% of adults, impairs blood flow to the legs and feet, often leading to pain, ulcers, and in severe cases, amputations. Unfortunately, PAD is frequently diagnosed too late, limiting treatment effectiveness.

The study, published in the European Heart Journal—Imaging Methods and Practice, introduces an ultrasound-based technique to better assess blood flow in the extremities. Traditionally, the diagnosis involves the toe brachial index (TBI), a simple, non-invasive test measuring blood pressure differences between the arm and toes. However, TBI can sometimes produce unreliable results, especially in patients with diabetes.

Researchers examined 155 limbs undergoing PAD treatment using a Doppler ultrasound waveform to estimate the toe brachial index (eTBI). This new method proved to be faster, more consistent, accurate, and accessible compared to the conventional TBI test. Notably, eTBI yielded reproducible results across different healthcare professionals and equipment, and it correlated well with treatment outcomes.

Professor Christian Heiss, lead researcher and Professor of Cardiovascular Medicine at the University of Surrey, explained, "This advancement could allow for earlier diagnosis of PAD, particularly in high-risk groups such as those with diabetes, potentially preventing serious complications like foot ulcers and amputations."

By enabling quicker and more reliable detection, this ultrasound approach offers a significant step toward better management and treatment of PAD, ultimately improving patient outcomes. For more details, the study can be accessed through DOI: 10.1093/ehjimp/qyaf057. This research underscores the importance of innovative diagnostic tools in enhancing cardiovascular health care.

Source: https://medicalxpress.com/news/2025-07-early-diagnosis-poor-blood-circulation.html