7 Sugar Substitutes Accelerate Cognitive Decline by 62%, Study Finds

New research links certain sugar substitutes to faster cognitive aging

Low-calorie sweeteners like aspartame, saccharin, and xylitol have been used since the early 1900s. While these additives are popular for their diet benefits, recent studies suggest they may pose risks to brain health.

A comprehensive study involving over 12,000 adults from Brazil over eight years found that those with the highest intake of artificial sweeteners experienced a 62% faster decline in cognitive functions such as thinking and memory compared to those consuming the least.

"A 62% faster decline means that people in the highest group of sweetener consumption experienced cognitive aging at a much quicker pace than expected, which could increase their risk of earlier impairment later in life," said lead researcher Dr. Claudia Kimie Suemoto.

Participants consuming large amounts of artificial sweeteners, averaging 191 mg/day, showed declines in cognition similar to aging 1.6 years more quickly. Notably, the fastest decline was observed in those under 60 and individuals with diabetes.

Why is this important?

The study suggests that even moderate or long-term use of these sweeteners might accelerate brain aging, especially during midlife, a critical period for long-term cognitive health. While causation isn't confirmed, the findings raise concerns over the habitual consumption of artificial sweeteners.

What experts say

Dr. Kamal Wagle emphasizes the need for further research to understand why these effects are more prominent in younger adults and those with metabolic conditions. The biological mechanisms behind this link remain unclear, but this study highlights the importance of cautious dietary choices.

How to reduce artificial sugar intake

Nutrition experts recommend conducting a "sweetener audit," tapering intake, and replacing artificial sweeteners with natural options like honey, maple syrup, or fruit. Mindful eating can help preserve natural taste sensitivities and reduce potential health risks.

For more tips on healthier alternatives, consult a registered dietitian and consider reducing processed food consumption containing artificial sweeteners.

Learn more about how diet impacts brain health and make informed choices for your cognitive longevity.