Innovative Silicone Models Revolutionize Medical Training and Research in Cerebral Vasculature

A groundbreaking development by Swiss Vascular, an ETH Zurich spin-off, has introduced highly detailed silicone replicas of cerebral blood vessels. These anatomically accurate models are crafted using advanced 3D printing techniques based on MRI and CT scans, representing both human and animal brains with remarkable precision. The goal of this innovation is to enhance medical training and reduce reliance on animal experiments, aligning with the principles of ethical research. The models' transparency enables practitioners to observe instrument placement in real-time, improving procedural accuracy and safety.

The inception of this technology stemmed from research in microcapsules designed to deliver targeted medicines, such as cancer treatments, through the complex vascular networks. ETH Zurich researchers, including doctoral students Fabian Landers and Pascal Theiler, discovered that practicing on these 3D printed models provides invaluable insight before moving to animal testing, ultimately contributing to the experiments' success.

Swiss Vascular’s models facilitate a variety of applications—from practicing neurosurgical procedures to testing medical devices—offering a significant advantage over traditional training tools that lack tissue elasticity and visibility. Made from synthetic materials that closely mimic real tissues, the models not only improve training outcomes but also promote more ethical research practices by reducing animal testing.

The company has seen rapid growth, driven by strong demand from research institutions and clinics worldwide, leading to its official founding in 2024. Their vision extends beyond modeling: plans are underway to develop comprehensive simulation platforms for continuous practice of complex medical procedures. This aligns with the 3R principles—Replace, Reduce, Refine—aiming to make medical research more ethical and efficient.

As part of their outreach, Swiss Vascular participates in initiatives like ETH Zurich’s 3R Day, demonstrating how these high-fidelity models can transform the future of medical training and research. Though challenges such as certification and commercialization remain, the pursuit persists for innovations that benefit research, clinical practice, and patient safety.