Significant Progress in RSV Immunization Among Infants: 72% Coverage Reported

A recent study published in the journal Pediatrics has revealed encouraging progress in the immunization of infants against respiratory syncytial virus (RSV), with 72% of infants having received some form of immunization. The research, conducted by Stephanie A. Irving and colleagues from Kaiser Permanente Center for Health Research, analyzed data from a large population of infants born between September 22, 2023, and March 31, 2024. The study utilized electronic health records and immunization systems to identify vaccination status, including antenatal maternal vaccination and receipt of nirsevimab, a monoclonal antibody used for RSV prophylaxis.

The study involved nearly 37,000 infants born to over 43,000 pregnancies. Findings showed a higher immunization rate among infants born to non-Hispanic Asian mothers, reaching 84%. In contrast, disparities emerged among different racial groups, with only 60% of infants born to non-Hispanic Black or Middle Eastern/North African mothers being immunized.

Coverage varied throughout the season, with more infants vaccinated earlier in the RSV season, and birth month played a role in immunization rates. Despite these positive trends, the authors noted that over 25% of infants remained unprotected, particularly among certain racial groups where up to 40% were not immunized.

The study underscores the need for addressing barriers to vaccination and reducing disparities to enhance protection against severe RSV infections in infants. Several authors disclosed ties to the pharmaceutical industry. Overall, these findings highlight significant progress but also emphasize ongoing challenges in RSV immunization efforts.

For more detailed insights, the full study can be accessed through Pediatrics (2025).