Innovative Online Test Detects Toxoplasmosis Without Blood Samples

A team of international researchers has introduced a groundbreaking online testing method capable of identifying toxoplasmosis infection without the need for blood or saliva samples. This advancement could significantly enhance epidemiological studies and understanding of how the parasite influences human behavior.

The test, developed by scientists including Dr. Michele Garagnani from the University of Melbourne, Carlos Alós-Ferrer from Lancaster University, and Anja Achtziger from Zeppelin University, assesses reaction times to determine if an individual is infected with the protozoan parasite Toxoplasma gondii, the cause of toxoplasmosis.

Traditionally, diagnosing toxoplasmosis required blood or saliva tests, which can be costly and logistically challenging for large-scale studies. The new online reaction time test offers a simple, non-invasive alternative. According to Dr. Garagnani, especially for individuals with RhD negative blood type, even a reaction time delay of less than a second could indicate infection.

Toxoplasmosis is transmitted mainly through exposure to cat feces or consuming raw or undercooked contaminated meat. It affects about 30% of the world's population, often without symptoms. However, research suggests that in some people, the infection can alter neurochemistry, affecting neurotransmitters like dopamine and serotonin, which in turn can influence behaviors such as impulsivity, risk-taking, and emotional regulation.

The research team validated their reaction-based test through a clinical trial involving 79 participants with RhD-negative blood type, achieving a 97% accuracy rate compared to traditional blood tests. They further surveyed over 1,000 individuals, finding that approximately 18% were likely infected. Data analysis revealed that infected individuals were more prone to unemployment, had lower incomes, and were more likely to engage in behaviors such as smoking and alcohol consumption. They also reported higher levels of mental health issues including anxiety and depression.

While the online test is not a substitute for medical diagnosis, it provides a valuable tool for large-scale studies on toxoplasmosis' behavioral effects. It offers a cost-effective way to estimate infection prevalence and understand its societal impacts, helping shape future public health strategies.

This innovative approach underscores the potential of digital tools in epidemiology and behavioral research, paving the way for better understanding and management of parasitic infections worldwide.

Source: https://medicalxpress.com/news/2025-07-online-toxoplasmosis-blood-sample.html