Natural Antioxidant Resveratrol Shows Promise in Combating Muscle Decline from Obesity
New research suggests that resveratrol, a natural antioxidant, could help preserve muscle strength and function in individuals affected by high-fat diets and obesity, offering promising avenues for future therapies.
Recent research conducted by Coventry University indicates that resveratrol, a natural antioxidant found in foods like red grapes and peanuts, may have a beneficial role in reducing muscle deterioration associated with high-fat diets often linked to obesity. The study, carried out by the university's Research Center for Physical Activity, Sport and Exercise Sciences (PASES), provides the first clear evidence that resveratrol can help preserve muscle strength and performance even under metabolic stress conditions.
Using advanced experimental techniques, researchers fed mice a high-fat diet over a period of 12 weeks, with some animals receiving a daily resveratrol supplement. The results revealed that mice supplemented with resveratrol exhibited significantly greater muscle power compared to those that did not receive the supplement. Remarkably, some of these mice demonstrated muscle functionality akin to animals on a healthier, standard diet, suggesting that resveratrol may offer a protective effect against diet-induced muscle decline.
The compound's effects were most pronounced in muscles responsible for quick, forceful movements, which are typically most impacted by high-fat diets. These findings open possibilities for future human trials, aiming to address the global obesity crisis affecting over a billion people. Maintaining muscle health could lead to substantial benefits, including disease prevention, improved quality of life, and enhanced mobility.
According to Associate Professor Jason Tallis, the project lead, this research marks a significant step forward in understanding how resveratrol can protect muscle performance under dietary stress. Professor Deborah Lycett highlighted the importance of this scientific advancement, emphasizing that such discoveries can pave the way for new treatments and strategies to combat obesity and related health issues.
Source: https://medicalxpress.com/news/2025-06-natural-antioxidant-muscle-decline-linked.html
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