Mounjaro Demonstrates Sustained Weight Loss Over 3 Years, Long-Term Study Confirms

Mounjaro Supports Long-Term Weight Management

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A recent study presented at the European Congress on Obesity (ECO) in Malaga, Spain, reveals that a once-weekly dose of tirzepatide (Mounjaro) can lead to significant and durable weight loss lasting up to three years in adults with overweight or obesity who do not have diabetes.

Key Findings:

• The treatment resulted in sustained weight reduction across a three-year period.
• Response to therapy varies by sex and presence of obesity-related health issues.
• Researchers identified three distinct weight loss patterns among participants.

Study Details:

The study involved 700 participants, primarily women, with an average age of 48 years, all of whom were either living with obesity or overweight and had prediabetes. Participants were grouped based on their weight loss trajectories:

• Group 1 (248 people): Steady loss (~10%), plateaued early.
• Group 2 (226 people): Rapid initial loss (~20%), plateaued later.
• Group 3 (226 people): Largest loss (~30%), longest time to plateau.

Insights into Weight Loss and Plateaus:

While weight loss plateaus are natural due to body mechanisms, most participants maintained significant weight reduction. The study highlights that even modest weight loss (5%) improves health markers, and greater losses (15%) yield more substantial benefits.

Expert Opinions:

Medical professionals acknowledge tirzepatide's effectiveness but emphasize the importance of ongoing support and patient education to sustain benefits. Variability in individual response underscores the need for personalized treatment plans.

Conclusion:

The findings support the use of tirzepatide as a long-term weight management tool and indicate that personalized strategies could enhance outcomes. Safety profile remains consistent with common side effects including nausea, diarrhea, and constipation.

For more insights, visit the European Congress on Obesity website or consult healthcare professionals familiar with this therapy.