Reducing Sedentary Time May Lower Alzheimer's Risk, New Research Finds

Sedentary lifestyles could be more harmful than previously thought. A recent study reveals that older adults who spend excessive time sitting or lying down are at increased risk for cognitive decline and brain shrinkage associated with Alzheimer’s disease, regardless of their exercise habits.

Key Findings

• Lifestyle factors like diet, sleep, no smoking, and exercise influence Alzheimer’s risk.
• The study emphasizes that prolonged sitting may negate the benefits of regular exercise.
• Genetic risk factors, such as the APOE-e4 allele, may amplify the harm of sedentary behavior.

Study Details

Researchers analyzed data from 404 participants aged 50 and above over seven years, using activity monitors and brain MRI scans. Findings suggested that even physically active individuals could be at risk if they spend too much time sitting.

Expert Opinions

Constance Katsafanas, DO, highlights that minimizing sedentary time might be crucial for maintaining brain health, even among those meeting physical activity guidelines. Experts agree that reducing sitting time is a practical strategy for lowering dementia risk.

Practical Tips

• Set timers to stand and stretch every 30-60 minutes.
• Take calls while walking.
• Incorporate social movement activities.

The Bottom Line

Addressing sitting habits, alongside regular exercise, could be an effective way to preserve cognitive function and reduce the risk of Alzheimer’s disease. As about 45% of dementia cases might be preventable, lifestyle modifications play a key role in brain health.

---

Sources: Medical News Today, Wiley, NIH, CDC, Harvard Medical School, The Lancet