Increased Risk of Cardiovascular Disease in Aging Individuals with Down Syndrome

As individuals with Down syndrome live longer, researchers have begun to examine how aging affects their health, particularly concerning cardiovascular conditions. Recent studies, including one published in the Journal of Internal Medicine, reveal that people with Down syndrome face a heightened risk of certain age-related cardiovascular diseases compared to the general population.

The study analyzed data from 5,155 individuals with Down syndrome born in Sweden between 1946 and 2000, comparing their health outcomes with matched controls based on sex, birth year, and birthplace. The findings indicated that individuals with Down syndrome are approximately 4.4 times more likely to suffer from ischemic stroke and over five times more likely to experience hemorrhagic stroke. Interestingly, the overall risk of heart attack was similar between those with Down syndrome and others; however, the risk was notably higher among younger individuals with Down syndrome.

These results emphasize that persons with Down syndrome have distinct cardiovascular risk profiles, which evolve as they age. Dr. Annie Pedersen from the University of Gothenburg highlights the importance of tailored surveillance and treatment strategies to manage and mitigate these risks. Recognizing these increased susceptibilities can aid healthcare providers in early detection and preventive care, improving quality of life for aging individuals with Down syndrome.

Understanding the intersection of Down syndrome and cardiovascular health is crucial as their life expectancy continues to rise. Ongoing research aims to develop specific guidelines ensuring holistic care for this population, addressing their unique health needs.