Global Link Between Plastic-Related Chemicals and Heart Disease Mortality

Recent research indicates that daily exposure to certain chemicals found in plastic household products may be responsible for over 365,000 deaths worldwide from heart disease in 2018 alone. The study, led by scientists at NYU Langone Health, focuses on phthalates—chemical compounds widely used to soften plastics like food containers, medical devices, and other flexible plastic items.

Phthalates, particularly di-2-ethylhexyl phthalate (DEHP), break down into microscopic particles that can be ingested, and are known to be present in many consumer products such as cosmetics, detergents, solvents, and bug repellents. Previous studies have linked exposure to these chemicals with various health issues, including obesity, diabetes, reproductive problems, and cancer. The latest analysis reveals a strong connection between DEHP exposure and increased risk of cardiovascular events.

The researchers estimated that DEHP contributed to approximately 368,764 deaths in 2018—more than 10% of global heart disease fatalities among individuals aged 55 to 64 years. The regions bearing the largest burden were Africa, East Asia, and the Middle East, with India alone accounting for nearly 40,000 deaths. These disparities are believed to be due to higher exposure levels in these regions, possibly linked to rapid industrial growth and less stringent manufacturing regulations.

The findings suggest that countries experiencing fast-paced industrialization and increased plastic consumption face significant public health challenges due to chemical exposure. Experts emphasize the importance of implementing stricter regulations to reduce phthalate exposure globally.

Although the study does not establish direct causality, the association underscores the urgent need to address the widespread use of phthalates in consumer products. Future research aims to explore how reducing exposure could lower mortality rates and expand understanding of other health risks posed by these chemicals.

This pioneering global assessment highlights the critical intersection between environmental chemicals and heart health, calling for concerted efforts to minimize risky exposures and protect public health.

source: https://medicalxpress.com/news/2025-04-heart-disease-deaths-worldwide-linked.html