Elevated DHEA-S Levels May Shorten Lifespan in Men, No Impact Observed in Women
New genetic research links higher DHEA-S hormone levels to shorter lifespan in men, highlighting gender-specific health effects and raising questions about supplement regulation.
Recent research indicates a significant link between higher levels of the hormone dehydroepiandrosterone sulfate (DHEA-S) and reduced lifespan in men. The study, led by Professor Mary Schooling from CUNY School of Public Health, employed a Mendelian randomization approach, analyzing genetic data from large European cohorts to determine causal relationships while minimizing confounding factors.
The findings revealed that genetically higher DHEA-S levels are associated with increased blood pressure and a shorter lifespan among men. Interestingly, the same connection was not observed in women, suggesting a gender-specific effect.
DHEA-S is a precursor to male and female sex hormones, such as testosterone, which implies that elevated levels could influence health outcomes differently across genders. The study's results align with FDA warnings about testosterone therapy potentially increasing blood pressure in men. These insights raise important questions about the regulatory status and over-the-counter availability of DHEA supplements in the United States.
While the evidence on DHEA-S and lifespan has been limited, this study provides robust genetic data supporting its impact on men's health. Further research is needed to explore potential interventions and guideline considerations regarding DHEA supplementation.
Source: Medical Xpress
Stay Updated with Mia's Feed
Get the latest health & wellness insights delivered straight to your inbox.
Related Articles
Long-Term Loss of Smell May Persist After COVID-19 Infection
New research reveals that the loss of smell following COVID-19 infection can persist for years and may often go unnoticed, impacting quality of life and health. Learn about the latest findings on post-COVID olfactory dysfunction.
Innovative Temporal and Noise-Resilient Methods Enhance Cardiovascular Imaging Accuracy
Discover how Hong Kong researchers have developed MemSAM, an AI model that improves echocardiography image segmentation by addressing noise and temporal consistency challenges, revolutionizing cardiovascular diagnostics.
Innovative Clinical Trial Enhances Detection of Hidden Blood Clots in Stroke Patients
A new clinical trial demonstrates that enhanced CT imaging including the heart greatly improves detection of blood clots in stroke patients, leading to better targeted treatments and stroke prevention.
Potential Risks of Taurine: Its Role in Promoting Leukemia Growth
Recent research uncovers the role of taurine in promoting leukemia growth by supporting cancer cell metabolism, highlighting the need for caution with taurine supplementation in at-risk individuals.