COVID-19 Vaccination During Pregnancy Leads to Improved Neonatal Outcomes Without Increased Maternal Risks
Research shows COVID-19 vaccination during pregnancy reduces infection risk and improves neonatal outcomes without increasing maternal health risks, supporting its safety and efficacy.
Recent research has demonstrated that COVID-19 vaccination during pregnancy offers significant health benefits for both mothers and their newborns, without adding health risks to the mother. An extensive analysis of over 1.2 million pregnant individuals revealed that vaccinated women experienced a 58% reduction in the risk of COVID-19 infection. Additionally, vaccination was linked to a decrease in adverse pregnancy outcomes, including an 8% lower chance of preterm birth before 37 weeks and a 34% reduction in preterm births before 28 weeks.
The study, titled "Safety and Efficacy of Maternal COVID-19 Vaccination During Pregnancy: Umbrella Review & Meta-Analyses," compiled data from 23 meta-analyses encompassing more than 200 studies. Conducted by researcher and Harvard University fellow Nikan Zargarzadeh, the review suggests that vaccination during pregnancy also lowers the risk of stillbirth by 25%, reduces the likelihood of neonatal intensive care admissions by 9%, and decreases the incidence of congenital anomalies by 17%. Importantly, no increased risks were observed concerning maternal health, including hospitalization, intensive care needs, gestational diabetes, hypertension, or pre-eclampsia.
The findings, shared during the American Academy of Pediatrics 2025 National Conference & Exhibition, reinforce the safety and benefits of COVID-19 vaccination for pregnant individuals. These results can provide valuable guidance for healthcare providers and pregnant women making informed vaccination decisions.
Source: https://medicalxpress.com/news/2025-09-covid-vaccination-pregnancy-neonatal-outcomes.html
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