Impact of Cardiovascular, Kidney, and Metabolic Health on Psoriasis Risk
Research shows that poor cardiovascular, kidney, and metabolic health increases the risk of psoriasis, especially among genetically predisposed individuals. Early detection and intervention are vital for prevention and improved life expectancy.
Recent research has revealed a significant link between poor cardiovascular, kidney, and metabolic (CKM) health and an increased risk of developing psoriasis. The study highlights that individuals with compromised CKM health—characterized by factors such as chronic kidney disease, cardiovascular issues, and metabolic disturbances—are more prone to psoriasis, especially if they possess a high genetic predisposition.
The research, conducted by Gang Zheng and colleagues from China Medical University and utilizing data from the UK Biobank involving over 390,000 participants, categorizes CKM health into five stages. The findings show that the hazard ratios for developing psoriasis rise progressively with worsening CKM stages: 1.21, 1.38, 1.64, and 1.72 for stages 1 through 4, respectively, compared to stage 0. Notably, participants with stage 4 CKM health and high genetic risk faced up to a 2.82-fold increased risk of psoriasis.
Furthermore, there was a notable additive interaction between advanced CKM stages and high genetic risk, emphasizing the compounded effect on psoriasis susceptibility. Advanced CKM health also correlated with a reduction in life expectancy—by approximately 2 years within the psoriasis-affected population.
These findings underscore the importance of early detection and intervention in CKM health to prevent psoriasis and improve overall longevity. Addressing metabolic and cardiovascular risks at initial stages could be a crucial step in reducing the burden of psoriasis and associated health complications.
For more detailed insights, the full study is published in the Journal of the European Academy of Dermatology and Venereology: DOI: 10.1111/jdv.20852.
Stay Updated with Mia's Feed
Get the latest health & wellness insights delivered straight to your inbox.
Related Articles
Innovative Approaches in Blood Cancer Research Focused on Mutation Identification for Better Management
Researchers at the University of Cincinnati are pioneering mutation identification techniques to develop targeted therapies and make blood cancer a more manageable disease, accelerating progress through innovative lab and clinical collaborations.
Declining Use of Benzodiazepines Among Older Adults Post-Hospitalization Offers Hope but Risks Persist
Recent studies reveal a decline in benzodiazepine use among older adults post-hospitalization, yet many continue long-term use with associated health risks such as falls and dependence. Preventative strategies are essential to improve safety.
New Daily Oral Medication for Endometriosis Soon Available on the NHS: How Linzagolix Works
A new oral medication, linzagolix, has been recommended by NICE for the treatment of endometriosis. This innovative drug offers hope for women suffering from painful symptoms and infertility, providing a tailored, reversible, and effective option when other treatments fail.
Rising Wait Times for Emergency Hospitalization: A Growing Concern
A new study reveals that wait times for emergency hospitalization have increased significantly, with many patients experiencing delays of over 24 hours, raising concerns about patient safety and healthcare system capacity.