Innovative Visual Anagrams Enhance Brain Research Using AI-Generated Images

Scientists use AI-generated visual anagrams—images that change meaning when rotated—to study human perception, bridging gaps in understanding size, animacy, and emotional responses.
Recent advancements in artificial intelligence have allowed researchers at Johns Hopkins University to develop groundbreaking visual stimuli known as "visual anagrams." These images are designed to look like one object from a certain perspective and transform into a completely different object when rotated. This innovative approach addresses a long-standing challenge in perception science: creating standardized, controllable stimuli that can be used to study how humans process complex visual information.
The researchers utilized AI tools to craft these images, including representations that appear as both a bear and a butterfly, an elephant and a rabbit, or a duck and a horse, depending on the image’s orientation. The primary goal is to isolate specific perceptual effects—like size, animacy, or emotional response—by observing how people interpret these ambiguous images.
"These images are pivotal because they enable us to explore effects that were previously hard to study, such as size perception, in a highly controlled manner," explained Tal Boger, a Ph.D. student involved in the project. The team conducted experiments to examine how visual size preferences persist even when the same image is rotated, revealing that perception of real-world size influences aesthetic judgment regardless of orientation.
The creation of visual anagrams opens new avenues for studying both perception and cognition. For instance, the researchers propose that similar techniques could be used to differentiate how the brain processes animate versus inanimate objects, with images that switch between a truck and a dog when rotated.
Published in Current Biology, these findings highlight the potential of AI-generated stimuli to revolutionize experimental design in neuroscience and psychology. Future studies aim to utilize this approach to dissect various perceptual effects and understand the neural mechanisms underlying visual processing.
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