Vagus Nerve Stimulation May Boost Exercise Capacity and Reduce Inflammation

A new study finds that non-invasive vagus nerve stimulation can increase exercise capacity, lower inflammation, and potentially help individuals with heart conditions improve their overall fitness and quality of life.
Recent research has demonstrated that stimulating the vagus nerve—a critical nerve linking the brain to various organs, including the heart—could enhance physical fitness and exercise performance. Published in the European Heart Journal, this study explores how a non-invasive device, when used for just 30 minutes daily over a week, can improve oxygen uptake and key exercise measures.
The innovative device delivers gentle electrical impulses to activate the vagus nerve, resulting in increased oxygen consumption and improved cardiovascular responses during exercise. Participants who used the stimulator showed a 4% increase in oxygen uptake, along with an increase in maximum breathing rate and heart rate, allowing them to exercise more intensely.
The study involved 28 healthy volunteers, with half wearing the device attached to their outer ear daily for a week, and the other half using a placebo device. After a two-week washout period, each participant tested both devices. Blood analysis of some participants revealed lowered levels of inflammation after using the vagus nerve stimulator, indicating potential anti-inflammatory benefits comparable to physical activity.
The researchers from University College London and Queen Mary University of London suggest that this technology could especially benefit individuals with conditions like heart failure, where vagus nerve activity tends to be diminished. Heart failure patients often experience fatigue, breathlessness, and reduced ability to perform daily activities. This device may help improve their exercise tolerance and overall quality of life.
Dr. Gareth Ackland of Queen Mary University emphasized that enhancing vagus nerve activity could be a promising tool to boost fitness and reduce systemic inflammation. While larger studies are ongoing, the initial findings point toward a revolutionary approach to supporting heart health and general well-being through nerve stimulation.
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