Exercise May Be as Crucial as Medication in Preventing Colon Cancer Recurrence

Exercise and Colon Cancer: A Promising Prevention Strategy

Could regular physical activity be more effective than drugs for preventing colon cancer recurrence? Recent research suggests it might be.

Key Points:

• Colorectal cancer is the third most common and second deadliest cancer globally.
• Standard treatments include surgery, radiotherapy, and chemotherapy.
• Post-treatment lifestyle modifications, particularly exercise, are increasingly recognized for their role in reducing recurrence.
• A recent study indicates that a structured exercise program can reduce recurrence risk by 28% and overall mortality by 37%.

According to the World Health Organization, colorectal cancer accounts for 10% of all new cancer cases worldwide.

A Canadian-led study, published in The New England Journal of Medicine, involved 889 patients who had undergone treatment for stage 3 or high-risk stage 2 colon cancer. Participants who adhered to a supervised exercise regime experienced significantly better outcomes. Their risk of recurrence and death was notably lower than that of patients who received only health advice.

Experts suggest these findings highlight the potential for exercise to serve as a non-pharmacological, cost-effective strategy with fewer side effects. Dr. Julie Gralow from ASCO notes that exercise's benefits extend beyond cancer recurrence, improving overall health.

Implementing such programs broadly remains challenging due to logistical barriers, but integrating personalized exercise support into standard care could profoundly impact patient outcomes.

Supporting Evidence:

The CHALLENGE trial found that participants in an exercise program maintained higher survival rates and physical function over nearly eight years of follow-up. Researchers emphasize that exercise can be a powerful adjunct to traditional treatments, offering health benefits without the adverse effects associated with drugs.

implications

Healthcare systems should consider embedding structured physical activity programs into cancer care protocols. Tailored support and remote exercise options might overcome existing barriers, helping more patients benefit from this promising approach.