Potential Risks of Erythritol: How a Common Sugar Substitute May Impact Brain and Blood Vessel Health

Potential Risks of Erythritol: How a Common Sugar Substitute May Impact Brain and Blood Vessel Health

Just a single serving of an erythritol-sweetened beverage may harm brain and blood vessel health, according to a new cellular study.

Recent research suggests that higher levels of erythritol, a popular noncaloric sweetener, in the blood could be linked to increased risks of blood clotting, heart disease, and stroke. A new cellular study provides additional evidence that consuming just one serving of erythritol in beverages might negatively affect brain and vascular health.

Key Findings:

• Elevated erythritol levels are associated with a higher risk of vascular issues.
• Laboratory experiments show that erythritol increases oxidative stress and decreases nitric oxide production in brain blood vessel cells, potentially impairing blood flow.
• Experts recommend moderating erythritol intake and choosing safer alternatives like stevia or monk fruit.

How Erythritol Affects Brain and Blood Vessels

In laboratory studies, exposing human brain blood vessel cells to erythritol at amounts comparable to a single soda caused a significant rise in oxidative stress, with nearly double the reactive oxygen species (free radicals). This oxidative stress can damage cells and impair blood vessel function.

Additionally, erythritol hampers the production of nitric oxide, a molecule vital for blood vessel relaxation and proper circulation. This interference could contribute to neurovascular damage, increasing the risk of strokes and other vascular conditions.

Experts warn that while these findings stem from cellular research, they align with clinical data linking erythritol to cardiovascular risks. Moderation and alternative sweeteners are advised for health-conscious individuals.

Expert Recommendations

Healthcare professionals suggest limiting erythritol consumption and opting for natural sweeteners like honey or fruit-based syrups, which provide antioxidants. Non-nutritive sweeteners such as stevia and monk fruit are considered safer options as of now.

Ultimately, reducing overall reliance on artificial sweeteners and focusing on whole, nutrient-rich foods remains the best strategy for sustaining long-term brain and vascular health.