Innovative 'Montreal Model' Enhances Durability of Ketamine-Based Depression Treatment
The Montreal Model of ketamine therapy combines psychotherapy and supportive environments, leading to more sustained relief from severe depression and treatment resistance.
Recent clinical research led by McGill University introduces the 'Montreal Model,' a novel approach to ketamine therapy for severe depression. The study demonstrates that combining ketamine infusions with psychotherapy and a therapeutic environment significantly extends the duration of antidepressant effects. Participants with treatment-resistant depression, many experiencing suicidal thoughts, showed an average depression score reduction of approximately 30%, with improvements in suicidality and anxiety. Notably, these effects persisted for at least eight weeks, unlike conventional ketamine treatments where benefits often diminish within days.
The study emphasizes the importance of the treatment environment—rooms designed with calming lighting, plants, curated music or guided mindfulness—alongside regular psychotherapy sessions. This approach underscores the significance of psychological context in treatment outcomes.
Developed during residencies at McGill by Dr. Greenway and Dr. Garel, the Montreal Model integrates traditional psychiatry with strategies inspired by psychedelic therapy, including creating safe, supportive spaces for patients. The model has been successfully applied in both public and private healthcare settings in Canada and internationally.
An intriguing aspect of the research is the link between the subjective mystical or emotional experiences during ketamine sessions and positive therapeutic outcomes. These findings challenge the traditional view of such experiences as mere side effects, suggesting they may be integral to the healing process.
The study's positive results support the adoption of structured, environment-centric ketamine treatments, offering a promising path for managing complex, treatment-resistant depression. It also highlights the need for standardized protocols as ketamine clinics proliferate across Canada and beyond.
For further information, see the original source at
https://medicalxpress.com/news/2025-06-montreal-ketamine-therapy-yields-sustained.html
source: https://medicalxpress.com/news/2025-06-montreal-ketamine-therapy-yields-sustained.html
Stay Updated with Mia's Feed
Get the latest health & wellness insights delivered straight to your inbox.
Related Articles
Passive Screen Time and Its Connection to Anxiety and Mental Health Challenges in Teenagers
New research links passive scrolling on digital devices to increased anxiety and mental health issues among teenagers, emphasizing the need for better screen time management.
Children's Social Media Use Reflects Emotional Challenges of Managing Long-Term Health Conditions
A groundbreaking study reveals how social media activity highlights the emotional stress faced by children managing multiple long-term health conditions, emphasizing the need for holistic healthcare approaches.
Labor Day: Enhancing Social Connections Through Live Events
Discover how participating in live events during Labor Day can boost social connections and fight loneliness, supported by recent scientific research highlighted in a new study.
Social Engagement and Health in Older Adults: New Study Highlights the Importance of Strong Social Networks
A new study highlights the critical role of diverse and active social networks in supporting health and well-being among older adults, emphasizing the importance of fostering social connections to combat loneliness and improve quality of life.