A Simple Blood Test May Predict Your Lifespan and Healthy Aging

Researchers are developing a straightforward blood test that could evaluate your biological age, health span, and likelihood of longevity. This innovative approach uses DNA methylation patterns from blood or saliva samples to assess intrinsic capacity—a combined measure of mental and physical function vital for healthy aging.

What is Intrinsic Capacity?

According to the World Health Organization, intrinsic capacity encompasses all physical and mental abilities, including walking, thinking, seeing, hearing, and memory. Maintaining these capacities is crucial for healthy aging.

The New Assessment Method

Recent studies, including one published in Nature Aging, demonstrate that measuring DNA methylation patterns (epigenetic markers) provides an effective prediction of all-cause mortality and overall health. The so-called "IC clock" offers insights into biological aging beyond chronological age.

Key Findings

• Higher DNA methylation-based intrinsic capacity scores correlate with better lung function, mobility, bone density, and self-rated health.
• Individuals with higher IC scores tend to live about 5.5 years longer.
• The IC clock could serve as a valuable tool for tracking aging and guiding health interventions.

Can You Improve Your Intrinsic Capacity?

Dietary habits matter. Consuming oily fish rich in omega-3 fatty acids and limiting sugar intake support healthier epigenetic aging. Lifestyle choices like a balanced diet, regular exercise, and cognitive engagement also promote maintaining intrinsic capacity.

Expert Recommendations for Healthy Aging

Experts suggest following a nutritious diet (e.g., Mediterranean, MIND), engaging in regular physical activity, staying mentally and socially active, and managing stress and chronic conditions. These strategies help slow intrinsic capacity decline and improve lifespan quality.

This research marks a significant step forward in personalized aging medicine, offering a simple, noninvasive way to monitor and promote healthy aging.