Exposure to Mold Toxins During Pregnancy May Reduce Birth Weight via Placental Impact

Recent research from Rutgers University highlights a potential health concern for pregnant individuals: exposure to mycotoxins—a group of toxic compounds produced by mold—may adversely affect placental function, leading to lower birth weights in newborns. The study specifically focused on zearalenone, a mycoestrogen that mimics estrogen and contaminates food sources. Given its estrogen-like activity, zearalenone can interfere with hormonal processes vital for pregnancy and fetal development.

The researchers analyzed data from a cohort of pregnant women worldwide, discovering widespread exposure to mycoestrogens. They paid particular attention to genetic variations, such as the ABCG2 Q141K mutation, which influences the body’s ability to eliminate these compounds. Women carrying this variant showed altered pregnancy outcomes, suggesting genetics play a significant role in how environmental exposure impacts fetal health.

Zearalenone commonly contaminates grains and grain-based products like pasta, cereals, and baked goods, especially in ultra-processed foods. Since these foods are prevalent, pregnant individuals are encouraged to reduce consumption of heavily processed foods to minimize exposure. The study emphasizes the need for updated dietary guidelines and public health policies aimed at lowering mycoestrogen exposure, especially for genetically susceptible populations.

Additionally, climate change may amplify the problem as warmer temperatures increase the presence of mycoestrogens in crops globally. As awareness grows, future research aims to identify effective interventions to safeguard maternal and fetal health from these environmental toxins.

This study underscores the importance of considering both environmental factors and genetic predispositions in prenatal health strategies and highlights the need for ongoing surveillance of mycotoxin exposure during pregnancy.

Source: https://medicalxpress.com/news/2025-06-pregnancy-exposure-mold-toxins-linked.html