Maternal Selenium Levels During Pregnancy May Lower Risk of Childhood Streptococcal Infections

Recent research indicates that higher levels of selenium in pregnant women could be linked to a decreased risk of their children developing streptococcal infections, which are common bacterial illnesses in childhood. A comprehensive study conducted in Japan analyzed over 74,000 mother-child pairs from the Japan Environment and Children's Study. The scientists measured maternal blood levels of essential trace elements, including selenium, mercury, cadmium, lead, and manganese, and monitored the health outcomes of the offspring up to ages 3 and 4.

Findings revealed that children born to mothers with elevated selenium levels during pregnancy had a notably lower incidence of streptococcal infections, such as strep throat, skin infections, and more severe complications like scarlet fever. The association was strongest among mothers with the highest selenium concentrations. Selenium, a vital micronutrient known for its role in boosting immune function, appears to contribute to the development of a more resilient immune system in children.

However, researchers caution that excessive selenium intake can have toxic effects, emphasizing the importance of balanced consumption. The study's authors note that because selenium was measured from a single blood sample, further research is necessary to determine optimal intake levels and establish causality.

This study reinforces the potential importance of adequate selenium intake during pregnancy, which may support the immune health of children and reduce susceptibility to bacterial infections. Ongoing research aims to clarify how selenium influences immune mechanisms and to define safe, effective levels during gestation.

For more information, refer to the original study published in PLOS ONE: [DOI: 10.1371/journal.pone.0319356]. Source: https://medicalxpress.com/news/2025-05-selenium-exposure-pregnancy-childhood-streptococcal.html