Research Confirms Loneliness and Heart Disease Link Across Cultures

Recent findings highlight that the association between loneliness and increased risk of cardiovascular disease (CVD) is consistent across different cultural contexts, specifically in South Korea and the United States. Traditionally, loneliness has been recognized as a significant risk factor for CVD, particularly in Western countries where social norms tend to emphasize individualism. However, a comprehensive study utilizing large datasets from both countries has shown that this link persists regardless of cultural differences.

The research, led by Harold Lee, an assistant professor at Penn State University, analyzed data from over 21,000 participants collected over approximately 12 years. Despite cultural distinctions—South Korea’s collectivistic society which emphasizes group harmony and interdependence, versus the U.S.’s individualistic approach—the study found that lonely individuals in both nations had about a 15% higher likelihood of experiencing CVD.

Interestingly, the study revealed that the behavioral pathways relating loneliness to heart health differ slightly between cultures. In both countries, loneliness was associated with decreased physical activity and increased alcohol consumption, both of which contribute to heart disease. Smoking, however, was a mediating factor only in the U.S., where nearly 20% of participants with a history of smoking were more likely to be lonely.

The implications of this research suggest that combating loneliness can be an effective strategy for heart disease prevention across diverse populations. Simple social interactions—such as calling family or friends, meeting for meals, or engaging in community activities—are intuitive yet powerful tools to reduce feelings of isolation and mitigate associated health risks.

This cross-cultural investigation underscores the universality of loneliness as a health concern and emphasizes the importance of social engagement for cardiovascular health. Its findings advocate for tailored public health policies and clinical interventions that consider cultural nuances but also recognize shared human experiences.

Sources: https://medicalxpress.com/news/2025-05-link-loneliness-heart-disease-persists.html