Income Disparities Significantly Impact Liver Cancer Survival Rates

Recent research from the University of Gothenburg highlights a critical link between income levels and survival outcomes in patients diagnosed with hepatocellular carcinoma (HCC), the most common primary liver cancer. Annually, approximately 500 to 550 new cases of HCC are diagnosed in Sweden, with men accounting for about 75% of these cases. The study finds that individuals with low household income face about a 30% higher risk of death compared to those with medium or high incomes. This disparity is partly due to lower rates of early diagnosis and reduced access to curative treatments among lower-income groups.

The research team previously established that HCC is roughly five times more prevalent among low-income populations. This new investigation sought to understand how sociodemographic factors such as income, education, and ethnicity influence diagnosis, treatment, and survival. Findings reveal that patients from lower-income households are less likely to be diagnosed at an early stage, which diminishes the chance for curative options and contributes to increased mortality.

Led by Juan Vaz, a researcher at the Sahlgrenska Academy and Halland Hospital, the study underscores the importance of addressing socioeconomic inequalities in healthcare. "Socioeconomic differences are strongly linked to less favorable health outcomes at every stage of care for HCC patients in Sweden," said Vaz. He emphasizes the need for targeted efforts to ensure equitable healthcare access.

The study examined data from 5,490 adult HCC patients registered in Sweden’s National Liver Registry between 2011 and 2021. Socioeconomic information was obtained from national health and demographic databases, with adjustments made for underlying liver diseases, comorbidities, and tumor characteristics that could influence treatment decisions and prognosis.

A crucial aspect of the research involves developing strategies for targeted screening, especially in socioeconomically deprived areas. Since cirrhosis—a major risk factor for HCC—results from chronic liver inflammation due to factors like high alcohol intake and hepatitis infections, early detection can significantly improve outcomes. The team is employing advanced statistical approaches to identify high-risk areas for screening initiatives and plans to pilot these efforts.

"Targeted screening for liver cirrhosis in disadvantaged communities can facilitate earlier HCC diagnosis, increase access to curative treatments, and improve overall health outcomes," Vaz explained.

This study emphasizes the vital need to eliminate healthcare disparities to improve liver cancer prognosis and highlights the importance of proactive, community-based screening programs.

Source: https://medicalxpress.com/news/2025-05-liver-cancer-survival-income-disparities.html