Brain Care Score Indicates Risk for Heart Disease and Common Cancers

Recent research from Mass General Brigham highlights the significance of the McCance Brain Care Score (BCS) as a predictor not only for brain-related conditions such as stroke, dementia, and depression but also for systemic health risks including cardiovascular disease and the three most common types of cancer worldwide—lung, colorectal, and breast cancers. The study demonstrates that individuals with higher BCS, which assesses modifiable lifestyle, physical, and social-emotional factors impacting brain health, tend to have a lower risk of developing these serious health issues.

The BCS, a 21-point tool developed at Mass General Brigham, encourages individuals to make small, meaningful changes to support brain health, which may concurrently benefit overall systemic health. The score considers factors like physical activity, nutrition, blood pressure, cholesterol, blood sugar levels, stress, and social engagement.

Investigating data from the UK Biobank involving over 416,000 adults aged 40 to 69, researchers found that a 5-point increase in BCS corresponded to a 43% reduction in cardiovascular disease risk and a 31% decrease in the incidence of lung, colorectal, and breast cancers over a median follow-up of more than 12 years.

While these findings reveal strong associations, they do not confirm causality. Nonetheless, the results support the concept that addressing shared risk factors can simultaneously improve brain, heart, and overall health. Experts emphasize that lifestyle modifications targeting these modifiable factors are crucial for disease prevention.

Lead researcher Dr. Jasper Senff notes that the BCS is a practical tool for primary care providers and individuals alike, helping identify achievable lifestyle adjustments. This multi-faceted approach not only promotes better brain health but also addresses broader chronic disease risks, making it a valuable addition to preventative health strategies.

The study underscores the common pathways linking brain health and systemic diseases, suggesting that caring for one's brain might be an effective way to also care for the heart and body, ultimately reducing the burden of preventable diseases and improving quality of life.